Of Coffee and Cirrhosis

Once again, a new study shows that coffee may contain an ingredient that protects us from yet another widely known disease of the liver - alcoholic cirrhosis. The comprehensive study, shows that among more than 125,000 people studied for up to 22 years, coffee drinkers were less likely to be diagnosed with alcoholic cirrhosis.

The researchers noted, “these data support the hypothesis that there is an ingredient in coffee that protects against cirrhosis, especially alcoholic cirrhosis.”

Of course, they aren’t recommending that anyone rely on drinking coffee to prevent alcoholic cirrhosis. After all, “not drinking heavily” is definitely a better strategy for liver health, the researchers emphasized.

The participants were signed up for the study between 1978 and 1985. They were followed until the end of 2001. Upon joining the group, participants were given a thorough checkup and was asked to fill out a complete report about their own consumption of alcohol, coffee, tea, and cigarettes. Most importantly, none had been diagnosed with liver problems.

Here’s a summary of the participants’ own report

* Most particiant were noted drinking light or moderate amounts of alcohol (up to two daily drinks).
* About 8% of them admitted drinking three or more alcoholic drinks per day.
* Typical coffee consumption was one to three daily cups, as reported by 42% of the group.
* Approximately 16% reported drinking four or more daily cups of coffee.

Over the years, 330 participants were diagnosed with cirrhosis; 199 of those cases were alcoholic cirrhosis, while the remaining cases of cirrhosis were nonalcohol related. Which means about 60% are related to alcohol drinking.

For every daily cup of coffee that participants reported drinking, they were 22% less likely to have been diagnosed with alcoholic cirrhosis during the study. Although the odds of developing nonalcoholic cirrhosis weren’t linked to coffee consumption.

Coffee drinkers were also less likely to have high blood levels of liver enzymes. That pattern was strongest in people with the highest reported alcohol consumption.

The study didn’t identify what ingredient in coffee might help protect the liver from alcoholic cirrhosis. Caffeine might not get the credit. Tea contains caffeine, but tea consumption didn’t appear to lower participants’ odds of being diagnosed with any form of cirrhosis.

Finally, the study doesn’t prove that drinking coffee cuts the chance of developing alcoholic cirrhoses, the researchers caution. They also point out that if coffee protects the liver, the effects of adding cream, milk, sugar, or other substances to coffee aren’t yet known.


SOURCES: 1. Klatsky, A. Archives of Internal Medicine, June 12, 2006; vol 166: pp 1190-1195.
2. Gloria Jean’s September 2007 e-newsletter.